The US Supreme Court was poised Wednesday to wade into the divisive battle over the abortion drug mifepristone with a ruling on tough new court-ordered restrictions on the widely used pill.

The nation’s highest court has until midnight Eastern Time (0400 GMT Thursday) to decide how it will handle the most significant abortion case since it tossed out the constitutional right to the procedure last year.

The panel can rule in any number of ways, and abortion rights and anti-abortion activists — as well as millions of Americans — are on tenterhooks waiting to see how the conservative-dominated court proceeds in the latest case involving women’s reproductive rights.

The case stems from a ruling this month by a US District Court judge in Texas that would have banned mifepristone, which was approved by the Food and Drug Administration in 2000 and accounts for more than half of all abortions in the United States.

An appeals court blocked a ban on the pill, but imposed tough restrictions on access, after which the baton was handed to the Supreme Court.

The Supreme Court, where conservatives wield a 6-3 majority, on Friday temporarily stayed the lower court rulings as it weighs what to do next.

The Supreme Court could decide to freeze the lower court rulings pending an appeal from the Justice Department and the mifepristone manufacturer Danco Laboratories.

It could also allow the rulings restricting access to the abortion pill to take effect while the appeals play out at the appellate level.

The court could also decide to hear arguments in the case itself on an expedited basis.

Complicating the case even further is a ruling by a separate federal court in Washington state that said access to mifepristone should be maintained.

Since the Supreme Court overturned the landmark Roe v. Wade ruling that enshrined the constitutional right to abortion for half a century, 13 states have banned abortion and it has been severely restricted in others.